孙嘉笛,博士,金沙检测线路js69副研究员,主要从事食品中食源性致病微生物和毒素的检测与控制研究。近年来围绕新型纳米材料合成、光电生物传感、合成表达识别元件的筛选及性能优化、微生物毒素控制技术等方面,以第一或通讯作者在Chemical Engineering Journal、Small、Biosensors and Bioelectronics、AnalyticalChemistry和Food Chemistry等主流期刊发表SCI论文20余篇。以主要发明人授权国家发明专利12件,授权国际发明专利1件,参与制定行业标准3项。参编《食品安全学——应用与实践》、《食品微生物检测技术》等教材3部。主持国家自然科学基金、“十三五”重点研发计划项目子课题、江苏省自然科学基金,中国博士后科学基金面上项目等国家和省部级科研项目。以第二完成人获得2020年中国商业联合会科技进步特等奖,以第一指导教师获得第十三届“挑战杯”中国大学生创业计划竞赛国家级银奖等多项奖励。
教育背景
1. 2015.09-2018.12:金沙检测线路js69,食品科学与工程,工学博士
2. 2017.12-2018.12:美国马萨诸塞大学,生物化学,联合培养
3. 2013.09-2015.09:金沙检测线路js69,营养与食品卫生学,硕转博
4. 2009.09-2013.06:天津工业大学,应用化学,理学学士
工作经历:
1. 2022.06-至今,金沙检测线路js69,副研究员
2. 2019.01-2022.05,金沙检测线路js69,助理研究员
1.国家自然科学基金面上项目,32472464,2025.01-2028.12,主持
2.十三五重点研发计划项目子课题,2021YFA0910204,2021.11-2026.10,主持
3.“十三五”重点研发计划项目子课题,2021YFC2101401,2021.7-2024.6,主持
4.江苏省自然科学基金青年项目,BK20190584,2019.07-2022.06,主持
5.中国博士后科学基金面上项目,2020M671343,2020.07-2022.09,主持
6.崇左市科技计划项目,FA2020014,2020.07-2022.09,主持
7.中央高校基本科研计划项目,JUSRP11906,2019.01-2020.12,主持
8.乳业生物技术国家重点实验室开放课题,SKLDB2019-005,2019.05-2021.04,主持
9.农业农村部农产品加工重点实验室开放课题,S2020KFKT-13,2020.08-2022.08,主持
代表性论文:
1.Bingqian Yu1, Qirui Liu1,Jiadi Sun*, Xuran Fu, Yinzhi Zhang, Xiulan Sun*. Phototherapy-based multifunctional nanoplatform for synergistic therapy against drug resistance bacteria: Progress, advances and challenges. Chemical Engineering Journal, 2024: 150705.
2.Xuran Fu1;Jiadi Sun1; Yongli Ye; Yinzhi Zhang; Xiulan Sun*.A rapid and ultrasensitive dual detection platform based on Cas12a for simultaneous detection of virulence and resistance genes of drug-resistantSalmonella. Biosensors and Bioelectronics, 2022, 195: 113682.
3.Qi Bao1;Jiadi Sun1; Xuran Fu; Lina Sheng; Yongli Ye; Jian Ji; Yinzhi Zhang; Jiasheng Wang; Jianping Feng; Xiulan Sun*. A Simplified Amplification‐Free Strategy with Lyophilized CRISPR‐CcrRNA System for Drug‐Resistant Salmonella Detection. Small, 2023, 19(29): 2207343.
4.Xuran Fu;Jiadi Sun*;BingqianYu; Yongli Ye; Lina Sheng; Jian Ji; Jiayu Zheng; Minghong Fan; Jingdong Shao; Xiulan Sun*. Investigating enzyme kinetics and fluorescence sensing strategy of CRISPR/Cas12a for foodborne pathogenic bacteria[J]. Analytica Chimica Acta, 2024, 1290: 342203.
5.Xuran Fu;Jiadi Sun*;Rong Liang; Hongyan Guo; Liping Wang; Xiulan Sun*. Application progress of microfluidics-integrated biosensing platforms in the detection of foodborne pathogens.Trends in Food Science & Technology, 2021, 116: 115-129
6.XuranFu,Jiadi Sun*,Bingqian Yu, Yongli Ye, Lina Sheng, Jian Ji, Jiayu Zheng, Minghong Fan, Jingdong Shao, Xiulan Sun*. Investigating enzyme kinetics and fluorescence sensing strategy of CRISPR/Cas12a for foodborne pathogenic bacteria. Analytica Chimica Acta, 2024, 1290: 342203.
7.Jiadi Sun; Xiulan Sun*.Recent advances in the construction of DNA nanostructure with signal amplification and ratiometric response for miRNA sensing and imaging. TrAC Trends in Analytical Chemistry, 2020, 127: 115900.
8.Jiadi Sun; Miao Li;Fuguo Xing;Haiming Wang; Yinzhi Zhang; Xiulan Sun*.Novel dual immunochromatographic test strip based on double antibodies and biotin-streptavidin system for simultaneous sensitive detection of aflatoxin M1 and ochratoxin A in milk, Food Chemistry, 2022, 375: 131682.
9.Jiadi Sun;Zhixuan Shi; Ting Zhang; Liangzhe Wang; Ruirui Dong; Yinzhi Zhang; Xiulan Sun*. Highly sensitive and quantitative fluorescent strip immunosensor based on an independent control system for rapid detection of tetrodotoxin in shellfish. Food Control, 2022: 109403
10.Jiadi Sun;Lu Gao; Liping Wang; Xiulan Sun*. Recent advances in single-cell analysis: Encapsulation materials, analysis methods and integrative platform for microfluidic technology. Talanta, 2021, 234: 122671.
11.Jiadi Sun1; Fuwei Pi1; Jian Ji; Hongtao Lei; Zhixian Gao; Yinzhi Zhang; Jean de Dieu Habimana; Zaijun Li; Xiulan Sun*.Ultrasensitive “FRET-SEF” probe for sensing and imaging microRNAs in living cells based on gold nanoconjugates, Analytical Chemistry, 2018, 90(5): 3099-3108.
12.Jiadi Sun;Wei Guo; Jian Ji; Zaijun Li; Xiao Yuan; Fuwei Pi; Yinzhi Zhang; Xiulan Sun∗. Removal of patulin in apple juice based on novel magnetic molecularly imprinted adsorbent Fe3O4@SiO2@CS-GO@MIP, LWT-Food Science and Technology, 2019, 118: 108854-108861.
13.Jiadi Sun; Fangchao Cui; Ruyuan Zhang; Zhixian Gao; Jian Ji; Yijing Ren; Fuwei Pi; Yinzhi Zhang; Xiulan Sun*. Comet-like heterodimers “gold nanoflower@ graphene quantum dots” probe with fret “off” to DNA circuit signal “on” for sensing and imaging microRNA in vitro and in vivo, Analytical Chemistry, 2018, 90(19): 11538-11547.
14.Jiadi Sun; Pei Zhu; Xiumei Wang; Jian Ji; Jean de Dieu Habimana; Jingdong Shao; Hongtao Lei; Yinzhi Zhang; Xiulan Sun*. Cell based-green fluorescent biosensor using cytotoxic pathway for bacterial lipopolysaccharide recognition. Journal of Agricultural and Food Chemistry, 2018, 66(26):6869-6876.
15.Kaimin Wei;Jiadi Sun*; Qing Gao; Xingxing Yang; Yongli Ye; Jian Ji; Xiulan Sun*. 3D “honeycomb” cell/carbon nanofiber/gelatin methacryloyl (GelMA) modified screen-printed electrode for electrochemical assessment of the combined toxicity of deoxynivalenol family mycotoxins. Bioelectrochemistry, 2021, 139: 107743.
16.Lu Gao;Jiadi Sun*;Liping Wang; Qigao Fan; Gaowen Zhu; Hongyan Guo; Xiulan Sun*. Highly sensitive real-time detection of intracellular oxidative stress and application in mycotoxin toxicity evaluation based on living single-cell electrochemical sensors. Analyst, 2021, 146(4): 1444-1454.
1.中国商业联合会科技进步特等奖,2020,排名第二
2.中国粮油学会科学技术一等奖,2021,排名第五
3.第十三届“挑战杯”中国大学生创业计划竞赛国家级银奖,2023年,指导教师(排1)
4.第七届中国国际“互联网+”大学生创新创业大赛国家级银奖,2021年,指导教师(排3)
5.江苏省研究生未来食品科研创新实践大赛省级一等奖,2021年,指导教师(排1)
1.Xiulan Sun,Jiadi Sun, Jian Ji, Yinzhi Zhang, Kaimin Wei, Cell Electrochemical Sensor Based on 3D Printing Technology and Application Thereof,US11,279,079 B2,
2. 孙秀兰,陆欣,孙嘉笛,张银志,纪剑,叶永丽,一种快速获得17β-雌二醇鼠源IgG全长抗体和Fab抗体的方法,发明专利,ZL202310184058.5
3. 孙秀兰,孙嘉笛,张银志,一种银包金纳米棒的制备方法及应用,发明专利,ZL201510044281.5
4. 孙秀兰,孙超,孙嘉笛,张银志,纪剑,一种快速有效降解粮食中脱氧雪腐镰刀菌烯醇的方法,发明专利,ZL201610403531.4
5. 孙秀兰,任奕婧,纪剑,孙嘉笛,皮付伟,张银志,一种细菌耐药性电化学检测方法,发明专利,ZL201910794286.8
6. 孙秀兰,纪剑,于坚,孙嘉笛,张银志,一株可快速同时降解三种真菌毒素的黑曲霉及其应用,发明专利,ZL2021106772316
7.孙秀兰,邹东,纪剑,孙嘉笛,叶永丽,张银志,一种黑曲霉菌株及其在赭曲霉毒素A降解中的应用,发明专利,ZL2021110806739
硕士生专业课《微生物与食品安全》
留学生专业课《学术论文规范与写作》
本科生专业课《食品安全学》